The Sperm DNA Fragmentation Test combined with a Spermatogram is a comprehensive male fertility evaluation designed to assess both standard semen parameters and the genetic integrity of sperm. Male factor infertility is involved in approximately 40–50% of infertility cases, making this combined test an essential part of fertility assessment when conception has not been achieved. The spermatogram is the foundation of male fertility testing and involves a complete analysis of semen according to World Health Organization (WHO) protocols. It evaluates semen volume, sperm concentration, motility, and morphology to assess overall sperm quality and fertilizing potential. The semen sample is obtained through masturbation into a sterile container and must be analyzed within the appropriate time frame to ensure accuracy. In addition to the standard semen analysis, the sperm DNA fragmentation test evaluates the integrity of sperm genetic material. This specialized test identifies breaks or damage in sperm DNA, which may not be detected through conventional semen parameters alone. DNA fragmentation testing is particularly valuable in cases of recurrent pregnancy loss, unexplained infertility, or repeated failures in assisted reproduction, as elevated DNA damage can negatively affect fertilization, embryo development, and pregnancy outcomes. Results from both tests are interpreted together by fertility specialists, recognizing that semen parameters represent statistical reference ranges and do not define absolute fertility. By combining structural semen analysis with genetic assessment, this service provides a more complete understanding of male reproductive potential and helps guide personalized treatment recommendations, including lifestyle changes, medical treatment, or the use of assisted reproductive techniques such as IVF with ICSI.